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MBF Bioscience neurolucida morphometry software
Neurolucida Morphometry Software, supplied by MBF Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/neurolucida+morphometry+software/neurolucida+morphometry+software/pmc10119172-126-34-37
Average 90 stars, based on 1 article reviews
neurolucida morphometry software - by Bioz Stars, 2026-10
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Microscopy:

Article Title: Chronic Low Dose Neutron Exposure Results in Altered Neurotransmission Properties of the Hippocampus-Prefrontal Cortex Axis in Both Mice and Rats.
Article Snippet: Brain sections were then mounted on gelatin-coated glass slides and cover slipped in Fluoromount G slide-mounting media (Southern Biotech, Birmingham, AL, USA). .. Neurons were manually traced and reconstructed in 3-dimensions with a 63×/1.4 N.A., Plan-Apochromat oil immersion objective on a Zeiss Axio Imager Vario microscope equipped with a motorized stage, video camera system, and Neurolucida morphometry software (MBF Bioscience, Williston, VT, USA). ..

Article Title: Sub-circuit alterations in dorsal hippocampus structure, and function after global neurodevelopmental insult
Article Snippet: .. Three measurements were taken for each layer ( stratum oriens , stratum pyramidale , stratum radiatum (str. rad.), stratum lacunosum moleculare (slm) , molecular layer, and granule cell layer) using the quick measure tool of Neurolucida morphometry software (version 11.11.2, Microbrightfield, Inc., Cholchester, VT) at 4× magnification using an Olympus BX5T microscope. .. rad.), stratum lacunosum moleculare (slm) , molecular layer, and granule cell layer) using the quick measure tool of Neurolucida morphometry software (version 11.11.2, Microbrightfield, Inc., Cholchester, VT) at 4× magnification using an Olympus BX5T microscope.

Article Title: Chronic Low Dose Neutron Exposure Results in Altered Neurotransmission Properties of the Hippocampus-Prefrontal Cortex Axis in Both Mice and Rats
Article Snippet: Brain sections were then mounted on gelatin-coated glass slides and cover slipped in Fluoromount G slide-mounting media (Southern Biotech, Birmingham, AL, USA). .. Neurons were manually traced and reconstructed in 3-dimensions with a 63×/1.4 N.A., Plan-Apochromat oil immersion objective on a Zeiss Axio Imager Vario microscope equipped with a motorized stage, video camera system, and Neurolucida morphometry software (MBF Bioscience, Williston, VT, USA). .. To be included in the analysis, a loaded neuron had to satisfy the following criteria: (1) reside within the pyramidal layer of the CA1 as defined by cytoarchitectural characteristics; (2) demonstrate complete filling of dendritic tree, as evidenced by well-defined endings; and (3) demonstrate intact tertiary branches, with the exception of branches that extended beyond 50 μm in radial distance from the cell soma [ , , ].Using NeuroExplorer software (MBF Bioscience) total dendritic length, number of intersections, and the amount of dendritic material per radial distance from the soma, in 30-μm increments [ ]. were analyzed in order to assess morphological cellular diversity and potential differences between the animal groups.

Article Title: Synaptic Plasticity Conveyed by the Intracellular Domain of Major Histocompatibility Class-I Proteins
Article Snippet: .. Neurons meeting these criteria were reconstructed in three-dimensions (3D) with a 40×/1.4 N.A., Plan-Apochromat oil immersion objective on a Zeiss Axiophot 2 microscope equipped with a motorized stage, video camera system, and Neurolucida morphometry software (MBF Bioscience, Williston, VT). .. Using Neurolucida Explorer software (MBF Bioscience) total dendritic length, number of intersections, and the length of dendritic material per radial distance from the soma, in 30 μm increments were analyzed in order to assess neuronal morphological diversity and potential differences among animals (30).

Article Title: Transgenic autoinhibition of p21-activated kinase exacerbates synaptic impairments and fronto-dependent behavioral deficits in an animal model of Alzheimer's disease
Article Snippet: .. Neurons were reconstructed and spines marked using an Olympus microscope equipped with a 63x objective (1.3 NA), a motorized stage, video camera system, and Neurolucida morphometry software (MBF Bioscience) by an experimenter blind to the experimental conditions. ..

Article Title: The intracellular domain of major histocompatibility class-I proteins is essential for maintaining excitatory spine density and synaptic ultrastructure in the brain
Article Snippet: .. Neurons meeting these criteria were reconstructed in three-dimensions (3D) with a 40 × /1.4 N.A., Plan-Apochromat oil immersion objective on a Zeiss Axiophot 2 microscope equipped with a motorized stage, video camera system, and Neurolucida morphometry software (MBF Bioscience, Williston, VT). .. Using Neurolucida Explorer software (MBF Bioscience) total dendritic length, number of intersections, and the length of dendritic material per radial distance from the soma, in 30 μm increments were analyzed in order to assess neuronal morphological diversity and potential differences among animals .

Software:

Article Title: Chronic Low Dose Neutron Exposure Results in Altered Neurotransmission Properties of the Hippocampus-Prefrontal Cortex Axis in Both Mice and Rats.
Article Snippet: Brain sections were then mounted on gelatin-coated glass slides and cover slipped in Fluoromount G slide-mounting media (Southern Biotech, Birmingham, AL, USA). .. Neurons were manually traced and reconstructed in 3-dimensions with a 63×/1.4 N.A., Plan-Apochromat oil immersion objective on a Zeiss Axio Imager Vario microscope equipped with a motorized stage, video camera system, and Neurolucida morphometry software (MBF Bioscience, Williston, VT, USA). ..

Article Title: Sub-circuit alterations in dorsal hippocampus structure, and function after global neurodevelopmental insult
Article Snippet: .. Three measurements were taken for each layer ( stratum oriens , stratum pyramidale , stratum radiatum (str. rad.), stratum lacunosum moleculare (slm) , molecular layer, and granule cell layer) using the quick measure tool of Neurolucida morphometry software (version 11.11.2, Microbrightfield, Inc., Cholchester, VT) at 4× magnification using an Olympus BX5T microscope. .. rad.), stratum lacunosum moleculare (slm) , molecular layer, and granule cell layer) using the quick measure tool of Neurolucida morphometry software (version 11.11.2, Microbrightfield, Inc., Cholchester, VT) at 4× magnification using an Olympus BX5T microscope.

Article Title: Chronic Low Dose Neutron Exposure Results in Altered Neurotransmission Properties of the Hippocampus-Prefrontal Cortex Axis in Both Mice and Rats
Article Snippet: Brain sections were then mounted on gelatin-coated glass slides and cover slipped in Fluoromount G slide-mounting media (Southern Biotech, Birmingham, AL, USA). .. Neurons were manually traced and reconstructed in 3-dimensions with a 63×/1.4 N.A., Plan-Apochromat oil immersion objective on a Zeiss Axio Imager Vario microscope equipped with a motorized stage, video camera system, and Neurolucida morphometry software (MBF Bioscience, Williston, VT, USA). .. To be included in the analysis, a loaded neuron had to satisfy the following criteria: (1) reside within the pyramidal layer of the CA1 as defined by cytoarchitectural characteristics; (2) demonstrate complete filling of dendritic tree, as evidenced by well-defined endings; and (3) demonstrate intact tertiary branches, with the exception of branches that extended beyond 50 μm in radial distance from the cell soma [ , , ].Using NeuroExplorer software (MBF Bioscience) total dendritic length, number of intersections, and the amount of dendritic material per radial distance from the soma, in 30-μm increments [ ]. were analyzed in order to assess morphological cellular diversity and potential differences between the animal groups.

Article Title: Synaptic Plasticity Conveyed by the Intracellular Domain of Major Histocompatibility Class-I Proteins
Article Snippet: .. Neurons meeting these criteria were reconstructed in three-dimensions (3D) with a 40×/1.4 N.A., Plan-Apochromat oil immersion objective on a Zeiss Axiophot 2 microscope equipped with a motorized stage, video camera system, and Neurolucida morphometry software (MBF Bioscience, Williston, VT). .. Using Neurolucida Explorer software (MBF Bioscience) total dendritic length, number of intersections, and the length of dendritic material per radial distance from the soma, in 30 μm increments were analyzed in order to assess neuronal morphological diversity and potential differences among animals (30).

Article Title: Transgenic autoinhibition of p21-activated kinase exacerbates synaptic impairments and fronto-dependent behavioral deficits in an animal model of Alzheimer's disease
Article Snippet: .. Neurons were reconstructed and spines marked using an Olympus microscope equipped with a 63x objective (1.3 NA), a motorized stage, video camera system, and Neurolucida morphometry software (MBF Bioscience) by an experimenter blind to the experimental conditions. ..

Article Title: The intracellular domain of major histocompatibility class-I proteins is essential for maintaining excitatory spine density and synaptic ultrastructure in the brain
Article Snippet: .. Neurons meeting these criteria were reconstructed in three-dimensions (3D) with a 40 × /1.4 N.A., Plan-Apochromat oil immersion objective on a Zeiss Axiophot 2 microscope equipped with a motorized stage, video camera system, and Neurolucida morphometry software (MBF Bioscience, Williston, VT). .. Using Neurolucida Explorer software (MBF Bioscience) total dendritic length, number of intersections, and the length of dendritic material per radial distance from the soma, in 30 μm increments were analyzed in order to assess neuronal morphological diversity and potential differences among animals .

Article Title: Socio-Ecological Disruptions at Critical Periods During Development Alter Stress Responses and Hippocampal Dendritic Morphology of Prairie Voles: Implications for Social Monogamy
Article Snippet: .. The slides were coded prior to image analysis with the Neurolucida morphometry software (MBF Bioscience). .. The images were acquired on a Zeiss Axiophot 2 microscope equipped with a motorized stage and a video camera, and the stained neurons were traced using a 40x/1.4N.A., PlanApochromat oil immersion objective.



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MBF Bioscience neurolucida morphometry software
Neurolucida Morphometry Software, supplied by MBF Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/neurolucida+morphometry+software/neurolucida+morphometry+software/pmc10119172-126-34-37
Average 90 stars, based on 1 article reviews
neurolucida morphometry software - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
MBF Bioscience neurolucida morphometry software (version 11.11.2
A) Golgi impregnated tissue was used to examine layer thicknesses, primary cell morphology, and spines. It can be seen from the tissue and the reconstructed neurons that the CA1 pyramidal layer is compressed in GD17-MAM rats. B) The hippocampus circuit receives its main input from the entorhinal cortex at both the molecular layer of DG (EC II) and in slm of CA1 (EC III). Information is transferred from DG to CA3 and then from CA3 to str. rad. of CA1. CA1 then acts as the main output of the hippocampus circuit. C) The stratum oriens, pyramidal and str. rad. of CA1 are significantly thinned in GD17-MAM rats compared to control rats (so: Group: t6 = 3.52; p = 0.01; pyr: t6 = 2.86; p = 0.03; str. rad.: t6 = 6.78; p < 0.001; slm: t6 = 1.75; p = 0.13; mol: t6 = 0.53; p = 0.61; grc: t6 = 1.40; p = 0.21. Control, n = 4; GD17-MAM, n = 4). D) Example <t>Neurolucida</t> reconstructions of granule cells from control and GD17-MAM rats (left panel) show similar cell morphologies. Dendritic length increases with distance from the cell body similarly in GD17-MAM and control rats (middle panel) and is not different between GD17-MAM and control rats in any sublayer of the molecular layer (right panel, inner mol: t30 = 0.70, p = 0.49; middle mol: t30 = 0.61, p = 0.55; outer mol: t30 = 0.23, p = 0.81). E) Branch order is also not different between GD17-MAM and control rats (1–3 branch order: t30 = 0.85, p = 0.40. ≥ 4 branch order: t30 = 0.28, p = 0.78. Granule cell neurons: Control, n = 16. GD17-MAM, n = 16). Spines were classified as thin, filipodia, mushroom, and stubby. In spite of similar overall morphology, GD17-MAM rats have an increased number of total spines per μm of branch length (thin: t46 = 1.25, p = 0.21; filipodia: t46 = 1.63, p = 0.11; mushroom: t46 = 0.75, p = 0.46; stubby: t46 = 1.13, p = 0.27; total: t46 = 2.39, p = 0.02. Branch segments: Control, n = 24; GD17-MAM, n = 24). F) Example Neurolucida reconstructions of CA1 pyramidal cells from control and GD17-MAM rats (left panel). Dendritic length of pyramidal neurons extends farther from the cell body in control rats (middle panel), and the total length within the str. rad. of CA1 is reduced in GD17-MAM rats while total branching in slm is not different (right panel, str. rad.: t23 = 2.30, p = 0.03. slm: t23 = 1.41, p = 0.17). Pyramidal neurons: Control, n = 14; GD17-MAM, n = 11. For D and F: Data is mean ± SEM for any concentric circle (distance from the neuron) that had more than 8 neurons. For all other graphs, data is mean ± SEM.
Neurolucida Morphometry Software (Version 11.11.2, supplied by MBF Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/neurolucida+morphometry+software/neurolucida+morphometry+software/pmc06278823-143-35-40
Average 90 stars, based on 1 article reviews
neurolucida morphometry software (version 11.11.2 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

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A) Golgi impregnated tissue was used to examine layer thicknesses, primary cell morphology, and spines. It can be seen from the tissue and the reconstructed neurons that the CA1 pyramidal layer is compressed in GD17-MAM rats. B) The hippocampus circuit receives its main input from the entorhinal cortex at both the molecular layer of DG (EC II) and in slm of CA1 (EC III). Information is transferred from DG to CA3 and then from CA3 to str. rad. of CA1. CA1 then acts as the main output of the hippocampus circuit. C) The stratum oriens, pyramidal and str. rad. of CA1 are significantly thinned in GD17-MAM rats compared to control rats (so: Group: t6 = 3.52; p = 0.01; pyr: t6 = 2.86; p = 0.03; str. rad.: t6 = 6.78; p < 0.001; slm: t6 = 1.75; p = 0.13; mol: t6 = 0.53; p = 0.61; grc: t6 = 1.40; p = 0.21. Control, n = 4; GD17-MAM, n = 4). D) Example Neurolucida reconstructions of granule cells from control and GD17-MAM rats (left panel) show similar cell morphologies. Dendritic length increases with distance from the cell body similarly in GD17-MAM and control rats (middle panel) and is not different between GD17-MAM and control rats in any sublayer of the molecular layer (right panel, inner mol: t30 = 0.70, p = 0.49; middle mol: t30 = 0.61, p = 0.55; outer mol: t30 = 0.23, p = 0.81). E) Branch order is also not different between GD17-MAM and control rats (1–3 branch order: t30 = 0.85, p = 0.40. ≥ 4 branch order: t30 = 0.28, p = 0.78. Granule cell neurons: Control, n = 16. GD17-MAM, n = 16). Spines were classified as thin, filipodia, mushroom, and stubby. In spite of similar overall morphology, GD17-MAM rats have an increased number of total spines per μm of branch length (thin: t46 = 1.25, p = 0.21; filipodia: t46 = 1.63, p = 0.11; mushroom: t46 = 0.75, p = 0.46; stubby: t46 = 1.13, p = 0.27; total: t46 = 2.39, p = 0.02. Branch segments: Control, n = 24; GD17-MAM, n = 24). F) Example Neurolucida reconstructions of CA1 pyramidal cells from control and GD17-MAM rats (left panel). Dendritic length of pyramidal neurons extends farther from the cell body in control rats (middle panel), and the total length within the str. rad. of CA1 is reduced in GD17-MAM rats while total branching in slm is not different (right panel, str. rad.: t23 = 2.30, p = 0.03. slm: t23 = 1.41, p = 0.17). Pyramidal neurons: Control, n = 14; GD17-MAM, n = 11. For D and F: Data is mean ± SEM for any concentric circle (distance from the neuron) that had more than 8 neurons. For all other graphs, data is mean ± SEM.

Journal: Brain structure & function

Article Title: Sub-circuit alterations in dorsal hippocampus structure, and function after global neurodevelopmental insult

doi: 10.1007/s00429-018-1704-3

Figure Lengend Snippet: A) Golgi impregnated tissue was used to examine layer thicknesses, primary cell morphology, and spines. It can be seen from the tissue and the reconstructed neurons that the CA1 pyramidal layer is compressed in GD17-MAM rats. B) The hippocampus circuit receives its main input from the entorhinal cortex at both the molecular layer of DG (EC II) and in slm of CA1 (EC III). Information is transferred from DG to CA3 and then from CA3 to str. rad. of CA1. CA1 then acts as the main output of the hippocampus circuit. C) The stratum oriens, pyramidal and str. rad. of CA1 are significantly thinned in GD17-MAM rats compared to control rats (so: Group: t6 = 3.52; p = 0.01; pyr: t6 = 2.86; p = 0.03; str. rad.: t6 = 6.78; p < 0.001; slm: t6 = 1.75; p = 0.13; mol: t6 = 0.53; p = 0.61; grc: t6 = 1.40; p = 0.21. Control, n = 4; GD17-MAM, n = 4). D) Example Neurolucida reconstructions of granule cells from control and GD17-MAM rats (left panel) show similar cell morphologies. Dendritic length increases with distance from the cell body similarly in GD17-MAM and control rats (middle panel) and is not different between GD17-MAM and control rats in any sublayer of the molecular layer (right panel, inner mol: t30 = 0.70, p = 0.49; middle mol: t30 = 0.61, p = 0.55; outer mol: t30 = 0.23, p = 0.81). E) Branch order is also not different between GD17-MAM and control rats (1–3 branch order: t30 = 0.85, p = 0.40. ≥ 4 branch order: t30 = 0.28, p = 0.78. Granule cell neurons: Control, n = 16. GD17-MAM, n = 16). Spines were classified as thin, filipodia, mushroom, and stubby. In spite of similar overall morphology, GD17-MAM rats have an increased number of total spines per μm of branch length (thin: t46 = 1.25, p = 0.21; filipodia: t46 = 1.63, p = 0.11; mushroom: t46 = 0.75, p = 0.46; stubby: t46 = 1.13, p = 0.27; total: t46 = 2.39, p = 0.02. Branch segments: Control, n = 24; GD17-MAM, n = 24). F) Example Neurolucida reconstructions of CA1 pyramidal cells from control and GD17-MAM rats (left panel). Dendritic length of pyramidal neurons extends farther from the cell body in control rats (middle panel), and the total length within the str. rad. of CA1 is reduced in GD17-MAM rats while total branching in slm is not different (right panel, str. rad.: t23 = 2.30, p = 0.03. slm: t23 = 1.41, p = 0.17). Pyramidal neurons: Control, n = 14; GD17-MAM, n = 11. For D and F: Data is mean ± SEM for any concentric circle (distance from the neuron) that had more than 8 neurons. For all other graphs, data is mean ± SEM.

Article Snippet: Three measurements were taken for each layer ( stratum oriens , stratum pyramidale , stratum radiatum (str. rad.), stratum lacunosum moleculare (slm) , molecular layer, and granule cell layer) using the quick measure tool of Neurolucida morphometry software (version 11.11.2, Microbrightfield, Inc., Cholchester, VT) at 4× magnification using an Olympus BX5T microscope.

Techniques: